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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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Tisolagiline methylsulfate is a selective, reversible, and orally active inhibitor for MAO-B with an IC50 of 8 nM. It exhibits neuroprotective and anti-neuroinflammatory activities. This product is for research use only and is not sold to patients.
IC50 & target: MAO-B: 8 nM (IC50)
In vitro: At 1 μM for 4 days, it inhibits astrocyte activation and scar formation by reducing glial fibrillary acidic protein (GFAP) and glycosaminoglycans (CSPGs) expression.
In vivo: In MPTP-induced Parkinson's disease mouse models, it ameliorates motor dysfunction and reduces GFAP/iNOS expression. In U87 MG xenograft models, it inhibits astrocyte scar formation, enhancing Doxorubicin penetration and increasing glioblastoma (GBM) tumor volume.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2'-Deoxy-L-guanosine is the L-configuration of 2'-deoxyguanosine, provided as a research-grade deoxynucleoside. It selectively inhibits D-thymidine phosphorylation catalyzed by herpes simplex virus 1 thymidine kinase and is intended for biochemical and antiviral studies requiring L-configured nucleoside analogs.
High purity: 99.3% by HPLC.
Suitable for biochemical and antiviral research applications.
L-configured deoxynucleoside, analog of deoxyguanosine.
Molecular formula C10H13N5O4; molecular weight 267.24 g·mol⁻¹.
Available in small research quantities, e.g., 10 mg.
Manufacturer documentation available: data sheet, SDS, and COA.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More